Waking the (Tiny) giant…

Nestled safely away within your cells, among your DNA, lies something…foreign. An invader. Something you weren’t born with, hidden, evading your immune system and waiting to make its next strike: a ‘latent’ virus. In all probability, there are armies of different viruses performing this same trick throughout your body. Remaining silent; some of their own mysterious accord, others kept in check by your immune system or by random mutations, rendering them useless. Now researchers at The Ohio State University and the University of Oxford have worked out how some of these viruses can reactivate in healthy people, and once again go about their nefarious mindless deeds: hijacking our cells machinery, producing more of their own kind, and causing disease. An inefficient virus kills its host. A clever virus stays with it. — James Lovelock In healthy people latent viruses aren’t generally a problem, occasionally annoying, but rarely life threatening. However, ...(Read More)

The “Dirty Little Secret”* About Vaccines

Note: This originally appeared on the SciBox section of the Oxford SciBar. Check out the site, there’s a host of podcasts of talks and other articles there.   In some ways, the immune system’s like a brain: it can learn, it can adapt and, so it’s ready for the next time, it can remember. This is, perhaps, its single most important feature. The immune system has the chance to learn a unique signature on the surface of an invader every time we’re infected by something, be it virus, bacteria or even a parasite. Once it learns these signatures the body produces antibodies or ’killer cells’ to fight it. When the infection has been defeated, special cells – B-cells – remember it, for as long as a life time. If the invader returns it won’t have such an easy time: the immune system will be ready. Like most things that learn, the ...(Read More)